In order to check the regions of interest for correct anatomical position, they were copied into the EPI T 2*-weighted scans acquired before contrast media application. Outlining regions of interest on corresponding anatomical T 2-weighted scans is not possible as EPI T 2*-weighted contrast-enhanced perfusion scans have a known geometric distortion. In each subject, regions of interest were outlined freehand bilaterally in white and in grey matter (frontal, parietal, occipital, striatal and thalamic) on CBV maps (Fig. RCBV and rCBF were calculated by a blinded investigator in regions of interest. brain, blood flow, regional mean transit time. ![]() In conclusion, nitrous oxide increases rCBF and rCBV predominantly in supratentorial grey matter, whereas isoflurane increases rCBF and rCBV predominantly in infratentorial grey matter. An increased rMTT was caused by a relatively greater increase in rCBV than in rCBF supratentorially by isoflurane and infratentorially by nitrous oxide. Isoflurane, by contrast, increased rCBF and rCBV in basal ganglia more than did nitrous oxide. Nitrous oxide increased rCBF and rCBV in supratentorial regions more than did isoflurane. In the present study, contrast-enhanced magnetic resonance (MR) perfusion measurement was used to compare the effects of 0.4 MAC nitrous oxide ( n=9) and 0.4 MAC isoflurane ( n=9) on regional cerebral blood flow (rCBF), regional cerebral blood volume (rCBV) and regional mean transit time (rMTT) in spontaneously breathing human volunteers. The use of isoflurane in neuroanaesthesia is widely accepted, whereas the use of nitrous oxide in neuroanaesthesia is still the subject of debate. Nitrous oxide and isoflurane have cerebral vasodilatory effects. Special Issue on Memory and Awareness in Anesthesia (PDF).Special Issue on Mass Casualty Medicine and Anaesthesia: Science and Clinical Practice (JPG).Special Issue on Thoracic Anaesthesia and Respiratory Physiology (PDF).Hong Kong College of Anaesthesiologists.College of Anaesthesiologists of Ireland.Memory, Awareness and Anaesthesia 2022 Special Collection.COVID-19 and the Anaesthetist: A Special Series.We’ll be happy to have you along for the journey. If you’d like to stay updated with what we’re working on, be sure to check out our new Tumblr blog, or follow us on Twitter. We’re already working on improvements for QuickCal 3.1 and I’m really excited about what’s coming down the pipe. This was the first Mac application I’ve designed and I’ve learned a ton. I’m also proud to announce the launch of the new QuickCal site, which I also had the pleasure of designing. I’m very proud to announce today that QuickCal 3.0 is available on the Mac App store. I wanted colour.Īfter a few rounds of revisions, and even more rounds of refinements and changes, we finally settled on a UI that would become QuickCal 3.0. I knew I wanted something simple, something that fit in with the OS X UI but didn’t just use standard UI elements. ![]() I began working on the app’s design immediately, churning out mockup after mockup in Photoshop. But, minutes later I was contacted by Jim Boutcher, the app’s creator, and by the end of the day I was invited to join the QuickCal team as the new UI designer. I posted a tweet that same day to the effect of “I wish I could get in touch with the QuickCal app devs to discuss redesigning their app for them.” I figured the tweet, like most of my tweets, would go unanswered. It was fast, it was simple, it used natural language to create events. I was beginning to wonder how I would find time to learn Objective C so I could create the app myself when my good friend Patrick Rhone pointed me to QuickCal. I wanted a simple app that would open with a keyboard shortcut, would let me enter the event using natural language, and would quickly get out of my way when the job was done. It was about 3 months ago when I was on the look out for a simple, fast way to add events to my iCal calendar.
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